下面上代码。
假设当前目录下有foo.xlsx/foo.jpg/foo.pdf/foo.mp3这4个文件。

import smtplib 
from email.mime.multipart import MIMEMultipart 
from email.mime.text import MIMEText 
from email.mime.application import MIMEApplication 
_user = "sigeken@qq.com" 
_pwd = "***" 
_to = "402363522@qq.com" 
 
#如名字所示Multipart就是分多个部分 
msg = MIMEMultipart() 
msg["Subject"] = "don't panic" 
msg["From"] = _user 
msg["To"] = _to 
 
#---这是文字部分--- 
part = MIMEText("乔装打扮，不择手段") 
msg.attach(part) 
 
#---这是附件部分--- 
#xlsx类型附件 
part = MIMEApplication(open('foo.xlsx','rb').read()) 
part.add_header('Content-Disposition', 'attachment', filename="foo.xlsx") 
msg.attach(part) 
 
#jpg类型附件 
part = MIMEApplication(open('foo.jpg','rb').read()) 
part.add_header('Content-Disposition', 'attachment', filename="foo.jpg") 
msg.attach(part) 
 
#pdf类型附件 
part = MIMEApplication(open('foo.pdf','rb').read()) 
part.add_header('Content-Disposition', 'attachment', filename="foo.pdf") 
msg.attach(part) 
 
#mp3类型附件 
part = MIMEApplication(open('foo.mp3','rb').read()) 
part.add_header('Content-Disposition', 'attachment', filename="foo.mp3") 
msg.attach(part) 
 
s = smtplib.SMTP("smtp.qq.com", timeout=30)#连接smtp邮件服务器,端口默认是25 
s.login(_user, _pwd)#登陆服务器 
s.sendmail(_user, _to, msg.as_string())#发送邮件 
s.close()