| 名次 | 片名 | 发行公司 | 全美总票房 | 首映票房 | 上映日期 | DVD发行日期 |
| 1 | 星战前传1：幽灵的威胁 Star Wars: Episode I - The Phantom Menace | 福克斯 | $431,088,301 | $,820,970 | 1999-5-19 | 2001-10-16 |
| 2 | 第六感 The Sixth Sense | 博伟 | $293,506,292 | $26,681,262 | 1999-8-6 | 2002-1-15 |
| 3 | 玩具总动员2 Toy Story 2 | 博伟 迪斯尼 | $245,852,179 | $57,388,839 | 1999-11-24 | 2005-12-26 |
| 4 | 王牌大贱谍2 Austin Powers: The Spy Who Shagged Me | 新线 | $206,040,086 | $54,917,604 | 1999-6-11 | 暂无 |
| 5 | 黑客帝国 The Matrix | 华纳 | $171,479,930 | $27,788,331 | 1999-3-31 | 1999-9-21 |
| 6 | 泰山 Tarzan | 博伟 | $171,091,819 | $34,221,968 | 1999-6-18 | 暂无 |
| 7 | 冒牌老爸 Big Daddy | 哥伦比亚 | $163,479,795 | $41,536,370 | 1999-6-25 | 暂无 |
| 8 | 神鬼传奇 The Mummy | 环球 | $155,385,488 | $43,369,635 | 1999-5-7 | 2001-4-24 |
| 9 | 落跑新娘 Runaway Bride | 博伟 派拉蒙 | $152,257,509 | $35,055,556 | 1999-7-30 | 暂无 |
| 10 | 女巫布莱尔 The Blair Witch Project | 艺匠 | $140,539,099 | $1,512,054 | 1999-7-16 | 暂无 |
| 11 | 精灵鼠小弟 Stuart Little | 哥伦比亚 | $140,035,367 | $15,018,223 | 1999-12-17 | 暂无 |
| 12 | 绿色奇迹 The Green Mile | 华纳 | $136,801,374 | $18,017,152 | 1999-12-10 | 2006-11-14 |
| 13 | 美国美人 American Beauty | 梦工厂 | $130,096,601 | $861,531 | 1999-10-1 | 2000-10-24 |
| 14 | 黑日危机 The World Is Not Enough | 米高梅 联美 | $126,943,684 | $35,519,007 | 1999-11-19 | 暂无 |
| 15 | 双重危机 Double Jeopardy | 派拉蒙 | $116,741,558 | $23,162,542 | 1999-9-24 | 暂无 |
| 16 | 新娘百分百 Notting Hill | 环球 | $116,0,678 | $21,811,180 | 1999-5-28 | 暂无 |
| 17 | 飙风战警 Wild Wild West | 华纳 | $113,805,681 | $27,687,484 | 1999-7-2 | 暂无 |
| 18 | 老大靠边闪 Analyze This | 华纳 | $106,885,658 | $18,383,507 | 1999-3-5 | 暂无 |
| 19 | 将军的女儿 The General's Daughter | 派拉蒙 | $102,705,852 | $22,332,053 | 1999-6-18 | 暂无 |
| 20 | 美国派 American Pie | 环球 | $102,561,004 | $18,709,608 | 1999-7-9 | 2001-7-31 |
| 21 | 无头谷 Sleepy Hollow | 派拉蒙 | $101,071,502 | $30,060,467 | 1999-11-19 | 暂无 |
| 22 | G型神探 Inspector Gadget | 博伟 | $97,403,112 | $21,8,138 | 1999-7-23 | 暂无 |
| 23 | 鬼入侵 The Haunting | 梦工厂 | $91,240,529 | $33,435,140 | 1999-7-23 | 暂无 |
| 24 | 将计就计 Entrapment | 福克斯 | $87,704,396 | $20,145,595 | 1999-4-30 | 暂无 |
| 25 | 宠物小精灵 Pokemon: The First Movie | 华纳 | $85,744,662 | $31,036,678 | 1999-11-10 | 暂无 |
| 26 | 危险人物 Payback | 派拉蒙 华纳 | $81,526,121 | $21,221,526 | 1999-2-5 | 2007-4-10 |
| 27 | 天才雷普利 The Talented Mr. Ripley | 派拉蒙 米拉麦克斯 | $81,298,2 | $12,738,237 | 1999-12-22 | 暂无 |
| 28 | 挑战星期天 Any Given Sunday | 华纳 | $75,530,832 | $13,584,625 | 1999-12-22 | 暂无 |
| 29 | 深海狂鲨 Deep Blue Sea | 华纳 | $73,8,228 | $19,107,3 | 1999-7-30 | 暂无 |
| 30 | 惊爆银河系 Galaxy Quest | 梦工厂 | $71,463,387 | $7,012,630 | 1999-12-25 | 暂无 |
| 31 | 天罗地网 The Thomas Crown Affair | 米高梅 | $69,304,435 | $14,600,719 | 1999-8-6 | 暂无 |
| 32 | 笨贼妙探 Blue Streak | 哥伦比亚 | $68,208,190 | $19,208,806 | 1999-9-17 | 暂无 |
| 33 | 末世浩劫 End of Days | 环球 博伟 | $66,8,403 | $20,523,595 | 1999-11-24 | 暂无 |
| 34 | 人骨拼图 The Bone Collector | 环球 | $66,518,655 | $16,712,020 | 1999-11-5 | 暂无 |
| 35 | 大制骗家 Bowfinger | 环球 | $66,458,770 | $18,062,550 | 1999-8-13 | 暂无 |
| 36 | 憨直舞男 Deuce Bigalow: Male Gigolo | 博伟 | $65,538,755 | $12,224,016 | 1999-12-10 | 暂无 |
| 37 | 傲笑江湖 Life | 环球 | $,062,587 | $20,414,775 | 1999-4-16 | 暂无 |
| 38 | 窈窕美眉 She's All That | 米拉麦克斯 | $63,366,9 | $16,065,430 | 1999-1-29 | 暂无 |
| 39 | 夺金三王 Three Kings | 华纳 | $60,652,036 | $15,847,636 | 1999-10-1 | 暂无 |
| 40 | 机器管家 Bicentennial Man | 哥伦比亚 | $58,223,861 | $8,234,926 | 1999-12-17 | 暂无 |
| 41 | 总有骄阳 The Cider House Rules | 米拉麦克斯 | $57,550,050 | $110,098 | 1999-12-10 | 暂无 |
| 42 | 大开眼界 Eyes Wide Shut | 华纳 | $55,691,208 | $21,706,163 | 1999-7-16 | 2007-10-23 |
| 43 | 一吻定江山 Never Been Kissed | 福克斯 | $55,474,756 | $11,836,707 | 1999-4-9 | 暂无 |
| 44 | 触电之旅 Forces of Nature | 梦工厂 | $52,957,800 | $13,510,728 | 1999-3-19 | 暂无 |
| 45 | 校园蓝调 Varsity Blues | 派拉蒙 | $52,4,169 | $15,204,108 | 1999-1-15 | 暂无 |
| 46 | 瓶中信 Message in a Bottle | 华纳 | $52,880,016 | $16,751,560 | 1999-2-12 | 暂无 |
| 47 | 南方公园 South Park: Bigger Longer & Uncut | 派拉蒙 华纳 | $52,037,603 | $11,335,8 | 1999-6-30 | 暂无 |
| 48 | 黑罪风云 The Hurricane | 环球 | $50,699,241 | $384,0 | 1999-12-31 | 暂无 |
| 49 | 天魔下凡 Stigmata | 米高梅 | $50,041,865 | $18,309,666 | 1999-9-10 | 暂无 |
| 50 | 猛鬼屋 House on Haunted Hill | 华纳 | $40,846,082 | $15,946,032 | 1999-10-29 | 暂无 |
